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Blaschko's lines
Blaschko, Alfred (1858 - 1922)
DIE NERVENVERTEILUNG IN DER HAUT IN IHRER BEZIEHUNG ZU DEN ERKRANKUNGEN DER HAUT.
Wien & Leipzig, Wilhelm Braumüller, 1901.
Folio [36 by 25 cm]. 54, [4] pp. + 26 plates.

Publisher's green cloth, gilt-lettered upper cover.
The copy of Magnus Möller [1857-1912], with his signature on front free endpaper.

$ 1000

First edition. Scarce. Includes bibliography (p. 26-9). Beilage zu den Verhandlungen der Deutschen Dermatologischen Gesellschaft VII. Congress zu Breslau im Mai 1902. Alfred Blaschko [1858-1922], German dermatologist,  credited for the first demonstration of the so-called Blaschko's lines, skin lines invisible under normal condition. They become apparent when some diseases of the skin or mucosa manifest themselves according to these patterns. They follow a "V" shape over the back, "S" shaped whorls over the chest, stomach, and sides, and wavy shapes on the head (cf. William M. Brown & Philip M. Brown, Transcription (London 2002). The lines are believed to trace the migration of embryonic cells (cf. Harper, John. Textbook of Pediatric Dermatology. p. 691, and Ruggieri, Martino (2008). Neurocutaneous Disorders: Phakomatoses & Hamartoneoplastic Syndromes. Springer. p. 569). The stripes are a type of genetic mosaicism (cf. Roach, Ewell S. (2004). Neurocutaneous Disorders. Cambridge University Press. p. 98). They do not correspond to nervous, muscular, or lymphatic systems. The lines can be observed in other animals such as cats and dogs (cf. Muller, George and Kirk, Robert (2001). Muller & Kirk's small animal dermatology. Elsevier Health Sciences. p. 9, and Gross, Thelma Lee (2004). Veterinary Dermatopathology. p. 156).

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